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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHAF1B All Species: 13.64
Human Site: T507 Identified Species: 20
UniProt: Q13112 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13112 NP_005432.1 559 61493 T507 I N L T P L K T D T P P S S V
Chimpanzee Pan troglodytes XP_525468 559 61460 T507 I N L T P L K T D T P P S S V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544875 668 72082 D617 N L I P L K T D T P P N S V P
Cat Felis silvestris
Mouse Mus musculus Q9D0N7 572 63114 T514 I N L T P L K T D T V P N P Q
Rat Rattus norvegicus NP_001019912 572 62715 A514 I N L T P L R A D T A P N P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512498 575 62833 P515 I S L M P L K P D P P A S D A
Chicken Gallus gallus Q5R1S9 566 62559 D514 T P A S V Y T D T V P V P P S
Frog Xenopus laevis Q8QFR2 1013 112021 S674 L T C V T T S S L T L R L P T
Zebra Danio Brachydanio rerio NP_998177 236 26626 Y186 A W D P L G Q Y I S T L S C D
Tiger Blowfish Takifugu rubipres O42611 1025 111838 S593 P S E R P K E S T P M Q K D V
Fruit Fly Dros. melanogaster NP_610589 747 83376 T561 E A V P P A E T S Q P A L A V
Honey Bee Apis mellifera XP_624307 452 51453 E402 I K S D I Y N E E S T N E V I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001191151 639 69080 Q545 P S N Q R P S Q N G G S P V T
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001132835 506 55177 D456 N K E P V T I D S M E V D A D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_974991 487 54088 K437 S K I T T D G K E K E H I M Q
Baker's Yeast Sacchar. cerevisiae Q04199 468 51234 H418 R I E P P A M H A E P L D T D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 73.8 N.A. 82.3 82.6 N.A. 75.6 72.7 20.9 33.6 20.6 35.7 38.6 N.A. 44.1
Protein Similarity: 100 99.8 N.A. 76.3 N.A. 88.4 88.4 N.A. 82 81.4 33 38.4 31.7 49.6 56.1 N.A. 58.2
P-Site Identity: 100 100 N.A. 13.3 N.A. 73.3 60 N.A. 53.3 6.6 6.6 6.6 13.3 26.6 6.6 N.A. 0
P-Site Similarity: 100 100 N.A. 20 N.A. 80 80 N.A. 60 13.3 20 20 33.3 46.6 26.6 N.A. 13.3
Percent
Protein Identity: N.A. 37.2 N.A. 35.6 25.7 N.A.
Protein Similarity: N.A. 53.1 N.A. 54.3 42.9 N.A.
P-Site Identity: N.A. 0 N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. 6.6 N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 0 0 13 0 7 7 0 7 13 0 13 7 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 0 0 7 7 0 7 0 19 32 0 0 0 13 13 19 % D
% Glu: 7 0 19 0 0 0 13 7 13 7 13 0 7 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 7 7 0 0 7 7 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 7 0 0 0 7 0 0 0 % H
% Ile: 38 7 13 0 7 0 7 0 7 0 0 0 7 0 7 % I
% Lys: 0 19 0 0 0 13 25 7 0 7 0 0 7 0 0 % K
% Leu: 7 7 32 0 13 32 0 0 7 0 7 13 13 0 7 % L
% Met: 0 0 0 7 0 0 7 0 0 7 7 0 0 7 0 % M
% Asn: 13 25 7 0 0 0 7 0 7 0 0 13 13 0 0 % N
% Pro: 13 7 0 32 50 7 0 7 0 19 44 25 13 25 7 % P
% Gln: 0 0 0 7 0 0 7 7 0 7 0 7 0 0 13 % Q
% Arg: 7 0 0 7 7 0 7 0 0 0 0 7 0 0 0 % R
% Ser: 7 19 7 7 0 0 13 13 13 13 0 7 32 13 7 % S
% Thr: 7 7 0 32 13 13 13 25 19 32 13 0 0 7 13 % T
% Val: 0 0 7 7 13 0 0 0 0 7 7 13 0 19 25 % V
% Trp: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 13 0 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _